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News > How Long Do CBD Gummies Stay In Your System?

How Long Do CBD Gummies Stay In Your System?

Thu, Jun 02, 2022 | Reading Time: 4 minutes

CBD gummies are one of the most popular types of CBD products on the market, and that’s not especially surprising when you take a moment to consider their benefits. CBD gummies make health and wellness fun! 


But all this popularity means you might have some questions. How long do CBD gummies stay in your system? How can you get them to stay in your system for as long as possible? What factors determine how long their effects last? 


Let’s take a closer look at these topics. Here’s an outline. 

  • How long does CBD stay in your system?
  • How long do CBD gummies stay in your system?
  • How to tell if your CBD gummies are high-quality

How long does CBD stay in your system?

CBD gummies may work differently than other types of CBD products, but they’re a CBD product nonetheless. 

And when it comes to CBD’s pharmacology — how quickly it stays in your system, and how long it stays there — there are a few almost universal concepts you should know about. 

  • CBD usually stays in your system for 3-5 days
  • That doesn’t mean you can feel it that long, though
  • The slower a CBD product kicks in, the longer it lasts for

A variety of factors affect how long CBD stays in your system. Here are a few of the most common ones, ranked from most important to least:

  • Your CBD dose 
  • What product you took
  • How often you’re taking it
  • Whether you’re taking CBD with absorption boosters

Let’s take a look at these factors on an individual basis. 


Factor 1: Your CBD dose

The easiest way to affect how long CBD stays in your system? Just change your dose. 


Larger doses of CBD take longer for your body’s endocannabinoid enzymes to break down, allowing this CBD to stay in your system for longer amounts of time. 


Smaller doses of CBD, on the other hand, don’t take as long for your body’s endocannabinoid enzymes to break down, meaning this CBD stays in your system for shorter amounts of time. 


Research is just beginning to back up this intuitive concept. One study found that a 100+ milligram dose of CBD stays in your system 2-3 times longer than a more ‘regular’ dose.  [1] A microdose may only stay in your system for a few hours — a macrodose is likely to stay in your system for days. 

Factor 2: What product you took

CBD’s lasting power also varies depending on the type of CBD product you’re taking. The faster a product kicks in, the faster it tends to leave your system. Products that kick in slowly tend to permeate the digestive tract so much that they stick around for awhile; products that kick in quickly tend to leave the bloodstream equally fast. The stats below should give you a better idea:


  • Vape pens: Kick in very fast / leave your system fast
  • Topicals: Kick in fairly fast / leave your system fairly fast
  • Edibles: Kick in slowly / leave your system equally slowly

CBD oil is one exception to this rule — it kicks in fast, yet leaves your system slowly. What gives? From a pharmacological perspective, CBD oil acts as two products in one. It acts as a sublingual when you hold it under your tongue, then switches over to a type of edible once you’ve fully ingested it. Sublinguals absorb straight into the bloodstream through the mouth’s mucous membranes, while the CBD in edibles only gets absorbed once it’s been processed by the liver. [2]

Factor 3: How often you’re taking it 

Most people don’t realize just how adaptable their body’s endocannabinoid system is. The more often you nourish this system with CBD and other cannabinoids, the more adept those same breakdown enzymes we mentioned earlier get at breaking said cannabinoids down. 


Translation: if you’ve been taking CBD for more than a month, it may not stay in your system for quite as long as it used to. If you’re brand new to CBD, on the other hand, even a small dose may stay in your system for longer than expected. [3]

Factor 4: Whether you’re taking CBD with absorption boosters

CBD’s solubility also gives us hints as to how long it might stay in your system for. Allow us to explain. Most natural compounds are either fat-soluble (aka they dissolve in fats/oils) or water-soluble (aka they dissolve in water). The beta-carotene in carrots, for example, is fat-soluble — otherwise you’d walk away from washing them with orange-stained hands. 


CBD is fat-soluble, too, which means that it absorbs best when taken alongside a little bit of fat. This effect is so pronounced that it even applies to what you eat. Taking a CBD gummy right after a fatty meal causes the CBD to kick in faster and be absorbed better. [4


Certain plant compounds can also improve CBD’s bioavailability. A compound found in black pepper called piperine is known to increase CBD’s absorption rates, which probably means it can increase how long the cannabinoid stays in your system, too.


Last but not least, other cannabinoids can help CBD stay in your system for longer. These cannabinoids are thought to help shuttle CBD to its most important molecular destinations through something that researchers call the entourage effect. Taking CBD with cannabinoids like THC, CBC, CBG, etc. may very well enable it to stay in your system for longer. 


(If this is all starting to sound a little complex, don’t worry. You don’t need to understand the entourage effect to benefit from it — all you need to do is take a full spectrum CBD product.)

How long do CBD gummies stay in your system?

fiveTM’s CBD Gummies stay in your system for roughly 3-5 days. Most customers can feel the effects of a single CBD gummy for 3-8 hours; after that, any amount of CBD remaining is typically sequestered into fat cells and no longer truly active. 


The slow onset time and even slower absorption of CBD gummies actually make them perfect for some groups. One practical benefit? Taking a CBD gummy each morning provides your body with enough timed-release CBD to get through the day. 


Another benefit? CBD gummies may provide extra relief to people with IBS or other digestive disorders, since the cannabinoids present in each gummy pass through the entire digestive tract as they get absorbed. 

How to tell if your CBD gummies are high-quality

So far we’ve covered how CBD works, how long CBD gummies tend to stay in your system, and how various factors can affect both topics. Now let’s move on and go over what you can expect to find in a truly long-lasting, premium CBD gummy!


First and foremost, be sure to opt for a truly full spectrum CBD gummy. This is more important than you might think. In addition to CBD, full spectrum CBD gummies will also contain a small — but significant — amount of THC. They’ll also contain trace cannabinoids like CBN and CBG. They’ll even include a hefty dose of terpenes. And the very best CBD gummies will include all these compounds in their original, natural ratios. Maybe we’re biased, but that’s exactly what we do with our gummies here at five™. 


Just as important as these must-haves is what’s not in a CBD gummy. Look for gummies that are verifiably free of artificial colors, artificial flavors, residual solvents, and mold. Bonus points for gummies that are vegan (or at least use plant extracts for color). 

Daily Buzz Gummies

  • How long do they stay in your system? 4-8 hours
  • Total cannabinoids per bottle: 500mg CBD + 100mg THC
  • Total cannabinoids per serving: 25mg CBD + 5mg THC
  • Flavor options: Blue Razz, Redberry, Lemon, Orange

If you’re looking for a buzz that’s strong enough to uplift but reserved enough to keep you functional, our Daily Buzz Gummies might be perfect for you. They’re just as great for powering through a busy day at work as they are for fostering a chill, laid-back evening. 

Original Gummies

  • How long do they stay in your system? 3-8 hours
  • Total cannabinoids per bottle: 500mg CBD + 40mg THC
  • Total cannabinoids per serving: 25mg CBD + 2mg THC
  • Flavor options: Blue Razz, Redberry, Lemon, Orange

If it’s not broke, don’t fix it — right? If you can resonate with that, our Original Gummies might be a great choice. They embody everything you’d hope to find in a premium gummy. Just a little lower in THC than the Daily Buzz variety, these gummies still offer plenty of CBD-powered chill. 

Sleep Gummies

  • How long do they stay in your system? 4-10 hours
  • Total active ingredients per bottle: 500mg CBD + 40mg THC + 60mg melatonin
  • Total active ingredients per serving: 25mg CBD + 2mg THC + 3mg melatonin
  • Flavor options: Berry

Our Sleep Gummies take an already-great CBD gummy base and add in enough melatonin to get you through the night. The presence of this sleep hormone allows them to last a little longer than most CBD gummies. Like CBD, melatonin possesses an incredible variety of protective effects above and beyond its ability to help you sleep better. 

Sour Gummies

  • How long do they stay in your system? 3-8 hours
  • Total cannabinoids per bottle: 500mg CBD + 40mg THC
  • Total cannabinoids per serving: 25mg CBD + 2mg THC
  • Flavor options: Sour Blue Razz, Sour Redberry, Sour Lemon, and Sour Orange

Do you find yourself content with the benefits of conventional CBD gummies, yet craving something a little…crazier? Then be sure to try our Sour Gummies. A single gummy is powerful enough to provide 3-8 hours of upliftment — and light up your taste buds.  

Daytime Rosin Gummies

  • How long do they stay in your system? 4-10 hours (estimated)
  • Total cannabinoids per bottle: 300mg rosin (mostly CBD and CBDa)
  • Total cannabinoids per serving: 15mg rosin (mostly CBD and CBDa)
  • Flavor options: Candied Lemon

We’ve partnered with The Botanist to create Daytime Rosin Gummies that pack a truly plant-powered punch. While more research is needed before we can say for sure, their ‘raw’ cannabinoid content (mostly CBDa and THCa) may allow them to stay in your system for far longer than conventional CBD gummies. 

Nighttime Rosin Gummies

  • How long do they stay in your system? 4-10 hours (estimated)
  • Total active ingredients per bottle: 300mg rosin, 60mg melatonin
  • Total active ingredients per serving: 15mg rosin, 3mg melatonin
  • Flavor options: Citrus

Our Nighttime Rosin Gummies pack a naturally plant-powered punch. Their ‘raw’ cannabinoids may allow them to stay in your system far longer than conventional CBD gummies do. As if that weren’t enough, these sleep-specific gummies also contain 3mg of melatonin each. Sweet dreams! 

Summing things up

All in all, what’s not to love about CBD gummies? They’re delicious, nutritious, and highly effective. They also stay in your system for long enough to turn an okay day into a good one…and turn a good day into something great. 


And if you want your CBD gummy of choice to stay in your system even longer, you can do that, too. Just up your dose, take your next gummy alongside a fatty meal, or opt for a CBD gummy that includes special ingredients like CBDa, THCa, or melatonin. Then get ready for 4-10 hours of all-natural bliss! (And don’t forget that a small amount of CBD will stay in your system for an additional 3-5 days.)

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